Jorgensen Laboratories, LLC 800.525.5614 | fax 970.663.5042 www.jorvet.com | [email protected] u How long should I freeze each lesion? Freezing times are based on the size and location of the skin lesion. For thin skin and sensitive areas such as the face, eyes, or ears, a freeze time of 20-25 seconds with a thaw time of 1 minute is desirable. For these sensitive areas, it is better to under-freeze versus over freeze. The treatment can always be repeated if necessary. Lesions that are 6mm or larger in size can be frozen for up to 40 seconds, with a thaw time of 1 minute. For larger, thicker lesions, up to 3 consecutive freeze-thaw cycles may be performed in the same visit, allowing a thaw time of 1 minute between each freeze. u I’m a first time user. Which product should I purchase first and how much does it cost? For first time users, we suggest purchasing the Cool Renewal Starter Kit (SKU J1401). This Kit will include two 170mL canisters of cryogen, instructions for use, practice materials, and all applicators. This kit will provide approximately 130 treatments, based on treating lesions 5mm in size. The retail cost of SKU J1401 is $400.00. Replacement canisters and applicators may be purchased separately at a lower cost. u What is the shelf life of Cool Renewal™? Does it expire or evaporate? Cool Renewal does not expire or evaporate, and has a minimum shelf life of 5 years from the time the canister is opened. u How do I store my Cool Renewal™ canister? Cool Renewal canisters should be stored at room temperature, and should not be subjected to temperatures over 100°F. Since Cool Renewal is packaged in an aerosol based canister, there is a pressure release valve located on the bottom. If the canister is subjected to temperatures above 100°F, there is a chance that this valve could be activated and all cryogen will expel from the canister. If you are planning to transport the canister in hot conditions, it is advisable to place the canister in a cooler or area where temperatures do not exceed 100°F. u How much do veterinarians typically charge for cryosurgical treatments? Typically, veterinarians charge a fee of $50-$75 per treatment without anesthesia. If anesthesia is required, the fees range from $150-$200. If there are multiple lesions to be treated on one patient, some veterinarians will charge a flat fee for the first lesion ($50), and a minimal fee ($10- $12) for each additional lesion. u Are there special shipping requirements or HAZMAT Fees? Because Cool Renewal is a non-flammable liquefied gas, it can only be shipped by ground service, ORM-D. There are no HAZAMT fees associated with Cool Renewal. For detailed shipping information, please contact Cool Renewal, LLC directly at 615.844.0132 or [email protected]. u Can I take Cool Renewal™ on an airplane? Cool Renewal CANNOT be taken onto an airplane in carry-on baggage; however it CAN be carried on an airplane in checked baggage. u How much revenue can I generate with Cool Renewal™? u What’s the difference between Cool Renewal™ & Verruca-Freeze®? Cool Renewal and Verruca-Freeze both use an aerosol based canister system and similar applicators. Cool Renewal fills the gaps of Verruca- Freeze by offering foam tipped applicators in six sizes, disposable isolation funnels in larger sizes for larger lesions, Skin Tag Tweezers that are unique to our system. Most importantly, Cool Renewal costs approximately 30% less than Verruca-Freeze, offering lower up- front costs with a lower cost per treatment. See Comparison Chart for more details. Cool Renewal offers a simplified range of products, making purchasing easy with low upfront costs. u Where can I find a SDS? A SDS sheet is included in the instructions for use and is provided with every Kit & Replacement Canister. The SDS sheet can be requested by email at [email protected]. TREATMENTS PER WEEK CHARGE REVENUE PER YEAR 1 $50.00 $2,600.00 2 $50.00 $5,200.00 3 $50.00 $7,800.00 4 $50.00 $10,400.00 5 $50.00 $13,000.00 6 $50.00 $15,600.00 7 $50.00 $18,200.00 8 $50.00 $20,800.00 9 $50.00 $23,400.00 10 $50.00 $26,000.00 TREATMENTS PER WEEK CHARGE REVENUE PER YEAR 1 $75.00 $3,900.00 2 $75.00 $7,800.00 3 $75.00 $11.700.00 4 $75.00 $15,600.00 5 $75.00 $19,500.00 6 $75.00 $23,400.00 7 $75.00 $27,300.00 8 $75.00 $31,200.00 9 $75.00 $35,100.00 10 $75.00 $39,000.00